Polynucleotide Treatments: The Regenerative Power of DNA Fragments

Article 9

Polynucleotides are quickly gaining popularity as one of the next generation treatments in medical aesthetics, offering a unique approach to skin revitalisation and cellular health. At Dr Adam’s practice, we will soon be introducing Polynucleotide treatments as part of our expanding portfolio of advanced skin treatments — alongside Exosomes and PRP.

What are Polynucleotides?

Polynucleotides are long, highly purified fragments of DNA — typically sourced from fish or salmon sperm — that work deep within the skin to stimulate cellular regeneration. By acting on fibroblasts (the skin’s collagen and elastin factories), polynucleotides:

✅ Enhance tissue repair
✅ Reduce inflammation
✅ Improve skin quality and hydration
✅ Minimise the effects of scarring or acne marks
✅ Support long‑term skin health

The Treatment Process: What to Expect

Polynucleotide treatments are administered via injections across targeted areas of the skin, making them ideal for treating delicate or dehydrated areas that don’t respond well to surface treatments.

• Duration: Approximately 30–45 minutes per session.
• Number of Sessions: A standard protocol involves three treatments, spaced roughly 3–4 weeks apart.
• Application Method: A fine needle or cannula delivers a sterile solution of DNA fragments precisely where needed.

What to Expect After Treatment

• Immediate: Minor redness, slight swelling, or small bumps (papules) may occur within 24–48 hours and typically resolve quickly.
• Results: Improvements in skin hydration and fine lines generally appear within 3–4 weeks and continue to evolve. The best results are typically seen around 12 weeks after the final session.

Why Choose Polynucleotides?

Polynucleotides stand out for their precision and long‑term benefits. They work at a cellular DNA level, making them ideal for patients seeking a targeted approach to:

• Maintain or restore skin health.
• Treat fine lines and thinning skin.
• Support overall collagen and elastin production.
• Enhance recovery after other treatments.

Interested in exploring how Polynucleotide treatments can support your skin health? Book a consultation with Dr Adam to learn more about these exciting treatments and how they can help you achieve long‑lasting, natural results.

Stay Tuned for Article 10: Making the Choice Right

With PRP treatments, Exosomes, and now Polynucleotides, it can be challenging to understand which option is best for your individual skin concerns.

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Stay tuned for article 10 of this series — an in‑depth comparison of PRP, Exosomes, and Polynucleotides, exploring their differences, benefits, and ideal applications, and helping you make the right choice for your skin.

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